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What are OPCs?

OPC is an abbreviation for "Oligomeric ProanthoCyanidins," natural health supporting compounds found in plants.  OPC's are concentrated in fibrous parts of fruits and vegetables and are often destroyed by cooking. OPCs are Powerful antioxidants.

Safety of OPCs

After more than 50 years of human use, no adverse effects have been observed. In one study, daily doses of up to 35,000 mg for six months were determined t o cause no adverse effects.

How is it taken?

Dr. Masquelier, who discovered OPCs in 1947, recommends using about 1.5 mg per pound of your body weight.

For Example:

Body Weight in Pounds	Amount in Milligrams (1 - 1.5)
100	100 to 150 mgs
200	200 to 300 mgs
300	300 to 450 mgs

Additional Health Benefits:

Aside from opcs role as a free radical scavenger and molecular protectant, it also helps "repair". It fights inflammation by inhibiting enzymes that cause pain in arthritis, sports injuries, and certain headaches. It restores joint flexibility. It strengthens all components of the cardiovascular system: heart, arteries, veins, and capillaries. Skin smoothness and elasticity is improved by realigning collagen fibers to a more youthful, undamaged form and increasing it's binding to elastin. 

Finally, OPCs reduce the effects of stress, improve sleep as well as sluggish memory and give you an overall sense of well being. All these benefits have been proven through detailed laboratory and clinical investigations in animals and in humans which have been published in foreign medical journal articles.

Grape Seed vs. Pine Bark

Grape seed and pine bark extracts are well-defined chemically. Both are excellent sources of proanthocyanidins: grape seed extracts are available which contain a total of 92% or 95% while the pine bark extracts can vary from 80% to 85%. Although both sources can be used interchangeably, for several valid reasons those extracted from grape seeds have emerged as the preferred source.

First of all, the overwhelming majority of the published clinical and experimental studies over the past twenty years have been performed on the grape seed extract, not the extract of pine bark. Professor Jacques Masquelier , the original patent holder for extraction procedures for both sources favours the grape seed extract not the extract of pine bark. It is also interesting to point out that only those extracted from grape seed are approved for medicinal use in France.

Studies by Professor Masquelier have demonstrated that the grape seed extract is substantially more potent and effective compared to the extract of pine bark. The reason? Only the grape seed extract contains the gallic esters of proanthocyanidins (in particular: proanthocyanidin B2-3'-0-gallate. These compounds are the most active free radical scavenging grape seed extract. They are not present in the pine bark extract.

And finally, it is far more economical to extract from grape seeds than it is from pine bark. As a result, the grape seed extract provides greater value at a lower price.

Laboratory studies have shown that grape seed contains antioxidants-substances that prevent cell damage caused by free radicals, which are highly reactive molecules that can damage cell function.

Pregnancy - are OPCs Safe?

Dr. Masquelier's clinical studies have been performed in which pregnant women who were troubled by varicose veins and other circulatory problems in the legs took OPCs. The product proved to be safe and worked very well.

What Is Grape Seed Extract?

Grape seed extract is a natural plant substance that has a concentrated source of oligomeric proanthocyanidins (OPC). These anti-oxidants help protect cells from free radical damage and also promotes healthy circulation. Grape Seed Extract is rich in polyphenols, a compound that's high in antioxidants. Studies have shown Grape Seed Extract to be a more powerful antioxidant than vitamin C, E, and beta-carotene.

Before Grape seed extract was discovered, the best sources of antioxidants came from vitamin C, E, and beta-carotene; however, these sources were not powerful enough to fight the free radicals and are also excreted by the body within a short time of ingestion. Grape seed extract, on the other hand, has been shown to remain in the body for as long as 3 full days, and is 20 times more potent than Vitamin C, and 50 times more stronger than Vitamin E.

How Does Grape Seed Extract Work?

The extract from the seed of these red grapes contains certain phenolic compounds called procyanidolic oligomers which are where the strong antioxidant abilities of the extract are located.

Grape seed extract is one of the most powerful antioxidants that fight free radicals

Grape seed extract is 20 times more potent than Vitamin C and 50 times stronger than Vitamin E

Grape seed extract helps improve cardiovascular health

It also helps promote brain, skin and eye health

Grape seed extract is also anti-bacterial, anti-viral, and anti-inflammatory

Grape seed extract is one of the few antioxidants that can penetrate the blood brain barrier to help protect the brain and nerve tissue

Some studies have also shown grape seed extract to prevent the formation of plaque in the arteries

It can also improve mental alertness and help prevent senility

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Grapes contain an extraordinary class of antioxidants – bioflavonoids called proanthocyanidins, that scavenge free radicals in the body. They also promote cellular health by neutralizing toxins and boosting the activity of detoxifying enzymes. Grapeseed Extract: * Promotes blood vessel health * Protects and strengthens veins, gums, bones and teeth * Reduces free radicals in the body * Promotes and Supports a Healthy Cardiovascular System Grapseed Extract promotes healthy blood pressure and cholesterol. These antioxidants promote blood vessel health by protecting the strength and flexibility of blood vessels, tissue cells, gums, bones and teeth. Strong and flexible collagen structures help keep the blood vessels elastic and resilient. Grape Seed Extract Details

 

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6 G. Block, University of Southern California at Berkeley
7 “ L e u c o a n t h o c yanins Extract From Grapeseeds (Vins Vinifera),” Indena Publication
8 Liviero, International Symposium on Phytochemistry of Plants Used in Traditional Medicine.
9 R.I. Rayer, and C. L. Schmidt, Seminary Hospital, (Paris: 1981), 57, 2009 and Indena International Report (Data on File).
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12 D. Zafirov, G. Bredy-Dobreva, V. Litchev, M. Papasovasvie, Ac ta Physiol Pharmacol, Inst i t u te of Phys i o l o g y, Bulgarian Academy of Sciences, (Sofia, Bulgaria: 1990) 16 (3) 50-54. 27
13 B. Vennet, “Anti-ulcer Activity of Procyanidin Preparation of Wa ter Soluble Pro c yanidin Cimetidine Comp l exes,” Pharm Acta Helv, (Switzerland: 1989), 64 (11) 316-20
14 “Leucoanthocyanins Extract From Grapeseed (Vins Vinfera)” Indena Publication. 28